Lium was reduced, although in a number of the alveoli, the thickness of epithelium was enhanced and replete with blood was observed (Figure 1). Histopathological study with toluidine blue staining revealed the reduction with the size and number of mast cells inside the handle group. Furthermore, alveolar sac and bronchioles with standard height epithelium have been noticed. In asthmatic group, thickness of alveolar epithelium, the size, and quantity of mast cells was considerably improved (p0.05). Moreover, a number of centers of hemorrhage in a few of alveolar sacs have been observed with presence of hemosiderin pigments. Within the P group which was treated with extract of p. major, the thickness of epithelium was recovered, the size along with the number of lymphoid cells have been less and scattered. Inside the theophylline group compared with the asthma group, the thickness of epithelium was lowered, but number and size of mast cells was similar for the asthma group (Figure 2). Histopathological study in the asthma group with PAS staining revealed that the glycoprotein compounds accumulates in airways and all of goblet cells in bronchioles were emptied and height of bronchiolar epithelium was elevated.173841-05-9 In stock Moreover, thickness of epithelium inside the alveoli was enhanced and also a large amount of largeAJP, Vol.261522-33-2 supplier three, No. two, SpringFarokhi et al.nodules around bronchioles were observed. Even though in the plantago groups, the bronchioles and air sacs had been related towards the manage group, meanwhile presence of lymphoid cells was much less and scattered. Inside the group treated with theophylline not just all of goblet cells in bronchioles werehevacuated compared with the manage group, but in addition presence of glycoprotein compounds in airways was conspicuous. The thickness of epithelium was reduced, but in some alveoli it was similar to asthma group (Figure 3).asf nbbCAfbfbas f as TPFigure 1. Cross sections of lung in experimental groups stained with H E, 40 C: Normal manage; A: Asthma group; P: Plantago group; T: Theophylline group; Lymphoid nodules (n); alveolar sac (as); epithelium (ep); hemorrhage (h); replete blood (f); bronchiole (b).PMID:23255394 ep b asasCALMPTFigure two. Cross sections of lung in experimental groups stained with toluidine blue, 400 C: Typical control; A: Asthma group; P: Plantago group; T: Theophylline group; epithelium (ep); mast cell (M); alveolar sac (as); bronchiole (b); lymphocyte (L).AJP, Vol. three, No. 2, SpringEffects of Plantago key on asthmaFigure three. Cross sections of lung in experimental groups, stained with PAS, one hundred C: Standard manage; A: Asthma group; P: Plantago group; T: Theophylline group; epithelium (ep); glycoprotein (gp); bronchiole (b); lymphatic nodule (n), goblet cell (g). This figure is displaying growing of glycoprotein compounds in bronchial of asthmatic and theophylline groups, though reduction of those symptoms in manage and plantago groups.Figure four. Cross section of bronchial in experimental groups with PAS staining, one hundred C: Normal handle; A: Asthma group; P: Plantago group; T: Theophylline group; Lymphoid nodules (n); goblet cell (g); bronchiole (b). As shown within this figure, within the handle group (b) bronchial was empty and devoid of any secretion compounds, but lots of goblet cells (g) with normal epithelium had been observed. Within the asthmatic group, bronchioles had been filled with glycoprotein compounds and height of epithelium was increased. Furthermore, a few lymphatic nodules (n) about bronchioles had been observed. Within this group, the majority of goblet cells were emptied. Inside the theophylline group, heig.